Science Article on Immune Markers of Long Covid
Our paediatric oncology applications lead, Sarah Brüningk, and our Ph.D. candidate, Bowen Fan, contributed data science analytics to support the identification of biomarkers of Long Covid. The relevant study, led by Dr. Carlo Cervia-Hasler, and Prof. Dr. Onur Boyman at University of Zurich, has been published in Science Magazine.
Their discoveries unveil potential biomarkers crucial for diagnosing and treating Long Covid. The researchers followed 113 COVID-19 patients for up to one year after their acute infection and compared them with 39 healthy individuals. After six months, 40 affected individuals still experienced symptoms implying a diagnosis of Long COVID. After analysing over 6500 blood proteins longitudinally, they found evidence of persistent complement-mediated immunopathology linked to altered coagulation , inflammation, and tissue injury in individuals experiencing Long Covid.
Long Covid is thus manifested by the protein pattern in the blood.
This is a significant step forward in our understanding of the virus and its long-term effects. We are sure they will continue working hard on finding ways to boost our immune system.
Great work team! And cheers for more successful collaborations! ☕
The scientific article of external page Brueningk S., et al. 2024.
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